CBN: Exploring the Research on CBN Benefits

CBN is SO hot right now… you might have already heard of it!  CBN Benefits are exciting people.

Let’s backtrack just a little. CBN is actually a subclass of cannabinoids. Cannabinoids are naturally occurring compounds that are found in the Cannabis plant. Other cannabinoids that you’ve already heard about are THC (Delta 8, Delta 9, Delta 10, etc.), CBG, and the big star, CBD. You’ve probably already used products that contain these compounds. Even further, chances are you have already been exposed to CBN, especially if you’ve used Broad and Full Spectrum products. 

CBN, also known as Cannabinol (ka-nuh-buh-naal), is a chemical compound that is mildly psychoactive, but won’t produce the high that you would experience with THC. This cannabinoid is flying hot into the market even though it was discovered all the way back in the 1930’s. CBN is created through the oxidation and decomposition of THC from a hemp plant – When THC gets hot and then exposed to Oxygen it will then convert to CBN. 

Yes, I get it – CBN pretty much comes from dead plants. That is one of the reasons, though, it has not been adequately researched… or researched much at all. Don’t sleep on this cannabinoid – because it actually may become one of the most utilized and effective cannabinoids. 


CBD and CBN are obviously similar as they are both cannabinoids and both serve as awesome anti-inflammatory products. They are both also very under-researched compared to how beneficial they can be to people and as relief of a multitude of ailments. 

One major difference is that CBD is non-psychoactive while CBN tends to be mildly psychoactive – still not nearly as much as THC, though. Since CBD is completely non-psychoactive, and occurs in much larger concentrations, it lends itself to be a more popular choice. CBN has many of the same benefits as CBD does. However, it’s unique effects are making it a major leader in natural sleep aids and a potential treatment option for diseases of the eye, such as glaucoma.


CBN is currently one of the most under-researched of the cannabinoids even with its growing popularity. There have been some rodent studies done with CBN, but not many recent scientific human studies. Though this is the case, people have been sharing their positive personal experiences with products that contain CBN. 


In early studies, scientists found that CBN has high levels of antibacterial properties. In one study conducted, CBN was used against strains of the MRSA bacteria, usually resistant to traditional antibiotics. CBN proved to be very potent as an antibacterial against these strains. Since MRSA is usually resistant, CBN may be effective against other infections as well. 


As with CBD and THC, some cannabinoids are slowly proving to contain neuroprotectant properties. Well, CBN is no different. In another early study, CBN showed to delay the onset of ALS in a group of rodents. It didn’t guarantee survival and only served as a treatment, further research could help with the treatment (and potential survival) of other neurodegenerative diseases. 

Appetite Stimulant

In 2012, one rodent study was conducted to research the effects of CBN on appetites. The study showed that Cannabinol is helpful in stimulating appetite without the major “high” effects of THC. This can be potentially helpful in stimulating appetites in people suffering from certain eating disorders and other people needing nutrients from food. 


As we’ve discussed in previous blogs, a lot of cannabinoids have shown to have powerful anti-inflammatory properties. CBN is no different. In 2016, this study showed that “As a class, the cannabinoids are generally free from the adverse effects associated with NSAIDs. Their clinical development thus provides a new approach to treatment of diseases characterized by acute and chronic inflammation and fibrosis”. 

Sleep Aid

Woman sleeping in bed after taking cbd and melatonin

CBN as a sleep aid seems to be one of the most popular reasons for using CBN products. Unsurprisingly, Melatonin (which I’m sure most of you have used or heard about) is the most comparable (and also natural) sleep aid on the market to CBN. Because of its helpfully sedative effects, you can find more and more CBD sleep products containing CBN. CBN on its own may not be effectively sedative but can be combined with other cannabinoids to create the entourage effect in order to produce the sleepy experience. 

CBN and Melatonin may work together well (just like CBD and CBN or CBD and Melatonin), providing the best sleep experience. As with all supplements, vitamins, and the like, be sure to use products that are right for you and work with you by talking to your doctor or by carefully experimenting on your own. 


Though CBN benefits are in the early stages of research (even compared to CBD and THC), CBN is still proving to be very beneficial in preventing and relieving a variety of ailments. InMed Pharmaceuticals is one of the leading companies to be conducting research on CBN and its effects on humans. 


One of the initial treatments InMed is looking to use CBN for is glaucoma in patients. Glaucoma is a disease that damages the patient’s eye’s optic nerve. As InMed is studying CBN, they state, “Of all of the cannabinoids examined, CBN demonstrated the most optimal effect of neuroprotection”. CBN can potentially be used for treating glaucoma in patients due to its neuroprotective properties and the ability to reduce intraocular pressure. 

Skin Integrity

Another study conducted by InMed was on the effects of CBN on skin integrity. More specifically, CBN’s effectiveness as a cream in healing open epidermal wounds and the safety of CBN on skin. By being able to use CBN as a safe cream in healing open wounds, it can be used as a treatment for people suffering from Epidermolysis bullosa, which causes fragile and blistering skin. 


What is CBN?

CBN is a cannabinoid that can potentially be used as an appetite stimulant, sleep aid, antibacterial agent, and other beneficial treatments.

Is CBN legal?

Under the 2018 Farm Bill, CBN is federally legal since it comes from hemp.

Is CBN right for me?

CBN could be beneficial for you. Talk to your doctor before introducing different supplements to your daily routine. You can also try experimenting with small doses and figure out how your body reacts to CBN.


Even though CBN is still being researched, demand is growing and growing. Consumers can find CBN in a multitude of products, even included in CBD, Delta 8, Delta 9, and Delta 10 products (in legal states, of course). As with any product, make sure you are purchasing your CBN products from a verified supplier with lab results available. 

When you are looking at CBN products for anti-inflammatory or antibacterial agents, a sleep aid or appetite stimulant, as a neuroprotectant, or other benefits, be sure to find what’s best for you. Talking to a doctor or experimenting with CBN products is important so you know how your body works with the cannabinoid. Let us know in the comments what CBN products you’ve tried and enjoyed!


Brie Lowrey, resident Head of Customer Engagement here at The Green Dragon CBD, is a Kansas City Native now residing in St. Louis. She thrives on keeping up with social media trends, staying up-to-date on CBD news, and sending out office-wide dragon jokes. Connect with her on LinkedInInstagram, or read other posts by Brie.

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